SDCASEA Webinar (4/3/2021, 2 pm PDT): COVID-19 Vaccine 專題研討會
合作夥伴
時間: 四月三日 下午2~4時 PDT
地點：Webex線上會議 (連結可在EventBrite註冊後取得)
形式：免費。本會議將以中文舉行 (Free attendance. This event will be conducted in Chinese Mandarin)
Talk 1: From COVID-19 Vaccines to Cancer Precision Medicine
Speaker Bio: Dr. I-Ming Wang received his B.S. in Biology from National Taiwan University, Ph.D. in Molecular Immunology from Baylor College of Medicine and post-doctoral training at the National Institutes of Health (NIH). He has 20 years’ experience working in the pharmaceutic industry. Before joining Pfizer in 2017, he spent 14 years at Merck as the Molecular Profiling Site Head at Merck’s West Point site in Pennsylvania focusing on Translational/Precision Medicine in multiple disease/functional areas including oncology, vaccine, infectious diseases, safety assessment, bioprocess and immunology. He currently serves as the Translational Oncology Lead at Pfizer for multiple phase 1 oncology clinical trials with assets including epigenomic drugs and targeted immunotherapeutics such as bi-specific antibodies, antibody-drug conjugates, cancer vaccines and oncolytic virus.
Abstract:
As of March 10, 2021, SARS-CoV-2 has infected more than 117 million people and caused 2.6 million deaths worldwide mostly in the elderly or people with pre-existing obesity, diabetes or cardiovascular conditions. Three COVID-19 vaccines, two highly effective mRNA-based and the other viral vector-based, have been developed in unprecedented record time and are being administered to the public; however, there are uncertainties about the long-term effectiveness and safety of these vaccines.
This seminar will cover the following topics:
- Characterization of the SARS-CoV-2 virus,
- General introduction about vaccines and how do they work,
- Development and efficacy of COVID-19 mRNA vaccines in clinical trials and in real world,
- Genetic and immunological determinants of severe COVID-19,
- COVID-19 vs. 1918 “Spanish” influenza pandemics and seasonal flu,
- SARS-CoV-2 variants and the next-generation COVID-19 vaccines, and,
- Potential therapeutic applications of mRNA technology, including cancer precision medicine.
Although COVID-19 caused extremely painful life and financial losses, it brought up an opportunity to demonstrate the strength and shortcoming of modern society to cope with global scale of health crises. In addition, it provided knowledge-seeking individuals a chance to delve into areas of cutting-edge novel medicine discovery and development. Hopefully, the world will learn from this traumatic event that close collaborations between public and private sectors and freely open sharing of critical scientific information relevant to disease control among nations are keys to prevent and mitigate future pandemic outbre
Talk 2: Operation Warp Speed (OWS) and the Production of COVID-19 Vaccines
Speaker Bio: Dr. Shaoyang Anthony Yeh is a researcher in industrial bioprocessing of vaccines and monoclonal antibodies. He is currently working as a process development scientist at Emergent Travel Health, Inc., located in San Diego, California. Previously, Shaoyang conducted process development projects at BioLegend, a global supplier for monoclonal antibodies. In his doctorate research, he focused on controlled drug release and three-dimensional (3D) tissue engineering. Shaoyang acquired an Engineering Science Ph.D. degree from the University of Oxford, a master’s degree in Biomedical Engineering from Cornell University, and bachelor’s degrees from the University of California, San Diego.
Abstract:
How did we come up with these vaccines in such a unprecedented short period of time? When can we achieve herd immunity? Many intriguing questions emerged since the day the virus arrived in our country. In response to this imperative, time-sensitive challenge, the US government went full-scale to adapt a research scheme that was never seen before–Operation Warp Speed (OWS). Various prototypic products were invested heavily, with collaborative support from academia, companies, government, and military, to help reopen the world. As vaccination starts to take place everywhere in this country, it is a suitable time to review what happened up until now and recognize the importance of many audacious designs that have reshaped the pharmaceutical industry.
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